Pharmacokinetics represents how the body processes the drugs after drugs entering the body, including drug absorption (A), distribution (D), metabolism (M), and excretion (E). Pharmacokinetics or biodistribution is presented as the trend of the concentration of the drug in the blood or tissues over time (concentration-time curve).
During the development of new drugs or new formulations, pharmacokinetics can provide important information for researchers to modify their drug design, as well as a reference for the frequency of dosing in the design of therapeutic efficacy studies. Pharmacokinetics is a necessary study for the development of new drugs, and it is also a necessary material for investigational new drug (IND) applications.
We use analytical chemistry, radioactive tracer, and molecular imaging technologies with good animal experiment design and execution to provide customized non-GLP pre-clinical pharmacokinetic studies, allowing researchers to explore the dynamics and behavior of the drugs in organisms. This pre-clinical pharmacokinetic data can serve as the reference for the design of the pharmacokinetic study in the future phase I clinical trial. We provide the animal pharmacokinetic information required by the researcher in the early stage of drug research and development, and assists in obtaining the data for GLP clinical trials and investigational new drug (IND) applications.
For relevant customized preclinical pharmacokinetics and biodistribution testing services, please contact us.
Types of drugs that can be analyzed:
* Small molecule drugs
* peptides
* Biologics such as proteins and antibodies
* Nanodrugs and nanocarriers
* Microparticles (microspheres)
* Cells
Analysis methods can be used:
* Liquid chromatography-tandem mass spectrometry, LC-MS/MS
* Enzyme-linked immunosorbent assay, ELISA
* Radioactive tracer technologies
* Molecular imaging technologies
Animal models:
* Mice, rats, and rabbits, etc. (Including normal and various disease animal models).
During the development of new drugs or new formulations, pharmacokinetics can provide important information for researchers to modify their drug design, as well as a reference for the frequency of dosing in the design of therapeutic efficacy studies. Pharmacokinetics is a necessary study for the development of new drugs, and it is also a necessary material for investigational new drug (IND) applications.
We use analytical chemistry, radioactive tracer, and molecular imaging technologies with good animal experiment design and execution to provide customized non-GLP pre-clinical pharmacokinetic studies, allowing researchers to explore the dynamics and behavior of the drugs in organisms. This pre-clinical pharmacokinetic data can serve as the reference for the design of the pharmacokinetic study in the future phase I clinical trial. We provide the animal pharmacokinetic information required by the researcher in the early stage of drug research and development, and assists in obtaining the data for GLP clinical trials and investigational new drug (IND) applications.
For relevant customized preclinical pharmacokinetics and biodistribution testing services, please contact us.
Types of drugs that can be analyzed:
* Small molecule drugs
* peptides
* Biologics such as proteins and antibodies
* Nanodrugs and nanocarriers
* Microparticles (microspheres)
* Cells
Analysis methods can be used:
* Liquid chromatography-tandem mass spectrometry, LC-MS/MS
* Enzyme-linked immunosorbent assay, ELISA
* Radioactive tracer technologies
* Molecular imaging technologies
Animal models:
* Mice, rats, and rabbits, etc. (Including normal and various disease animal models).